May 13, 2026

Sigma2 Receptors

As ERM proteins have been shown to interact with both positive and negative regulators of the Rho GTPase family, they may also regulate the exchange between Rab5 and Rab7 from the HOPS complex through their interaction with regulators of Rab GTPases
4 min read

As ERM proteins have been shown to interact with both positive and negative regulators of the Rho GTPase family, they may also regulate the exchange between Rab5 and Rab7 from the HOPS complex through their interaction with regulators of Rab GTPases

cmerp April 10, 2026
As ERM proteins have been shown to interact with both positive and negative regulators of the Rho...
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The Auto-Abs against the three proteins have high specificity, as indicated by the statistically significant stronger binding towards the peptides containing the three 6-mers (see Figure 1, -panel B and Outcomes) and by the IgG binding to 15-aa longer peptides containing the 6-mer epitopes flanked by irrelevant GS repeats (Figure S1)
4 min read

The Auto-Abs against the three proteins have high specificity, as indicated by the statistically significant stronger binding towards the peptides containing the three 6-mers (see Figure 1, -panel B and Outcomes) and by the IgG binding to 15-aa longer peptides containing the 6-mer epitopes flanked by irrelevant GS repeats (Figure S1)

cmerp February 19, 2023
The Auto-Abs against the three proteins have high specificity, as indicated by the statistically significant stronger binding...
Read More
Even though the confirmed PR rate was only 12% in the first 25 evaluable patients (all platinum-resistant patients), the 6-month PFS rate of 56% (14 of 25) met the efficacy criteria, justifying progression to second-stage accrual
6 min read

Even though the confirmed PR rate was only 12% in the first 25 evaluable patients (all platinum-resistant patients), the 6-month PFS rate of 56% (14 of 25) met the efficacy criteria, justifying progression to second-stage accrual

cmerp December 12, 2022
Even though the confirmed PR rate was only 12% in the first 25 evaluable patients (all platinum-resistant...
Read More

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