Month: October 2021

We used DAGL-tailored activity-based probes and chemical substance proteomic solutions to measure strength and selectivity of liposomal KT109 in macrophages and cells from treated mice

3 min read

• CCK Receptors

We used DAGL-tailored activity-based probes and chemical substance proteomic solutions to measure strength and selectivity of liposomal KT109 in macrophages and cells from treated mice

cmerp October 31, 2021

We used DAGL-tailored activity-based probes and chemical substance proteomic solutions to measure strength and selectivity of liposomal...

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A: Major murine astrocytes were isolated from 16

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• Cholecystokinin2 Receptors

A: Major murine astrocytes were isolated from 16

cmerp October 30, 2021

A: Major murine astrocytes were isolated from 16.5-day-old fetuses of wild-type C57BL/6 mice, treated with EGb 761...

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For lanes 8C10, T1 was incubated with concentrations of 20, 100, and 200?M, respectively

4 min read

• Glutamate (Kainate) Receptors

For lanes 8C10, T1 was incubated with concentrations of 20, 100, and 200?M, respectively

cmerp October 28, 2021

For lanes 8C10, T1 was incubated with concentrations of 20, 100, and 200?M, respectively. inhibitors that display...

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Lanes I and J represent control samples for GR expression in GC sensitive CEM cells and leukaemic blast cells, respectively

4 min read

• Cholecystokinin2 Receptors

Lanes I and J represent control samples for GR expression in GC sensitive CEM cells and leukaemic blast cells, respectively

cmerp October 27, 2021

Lanes I and J represent control samples for GR expression in GC sensitive CEM cells and leukaemic...

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Here, finding that inhibitory neurotransmitter glycine does not activate KCNQs, we re-engineered it in silico to expose expected KCNQ-opening properties, screened by in silico docking, then validated the hits in vitro

3 min read

• EP1-4 Receptors

Here, finding that inhibitory neurotransmitter glycine does not activate KCNQs, we re-engineered it in silico to expose expected KCNQ-opening properties, screened by in silico docking, then validated the hits in vitro

cmerp October 25, 2021

Here, finding that inhibitory neurotransmitter glycine does not activate KCNQs, we re-engineered it in silico to expose...

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Redox-dye reduction-based Phenotype MicroArray (PM) assays, which measure NADH decrease being a readout, produced by Biolog Inc

3 min read

• Sigma2 Receptors

Redox-dye reduction-based Phenotype MicroArray (PM) assays, which measure NADH decrease being a readout, produced by Biolog Inc

cmerp October 24, 2021

Redox-dye reduction-based Phenotype MicroArray (PM) assays, which measure NADH decrease being a readout, produced by Biolog Inc.,...

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CF?=?cleaved fragment (n?=?3) and (E) Immunofluorescence staining of apoptosis (TUNEL) display that VEDT induced apoptosis in (Mia-GFP) cells compared to vehicle (Veh) after 24?h and apoptosis was rescued in (Mia-FLIP) cells compared to vehicle (Veh) (n?=?3)

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• PKC

CF?=?cleaved fragment (n?=?3) and (E) Immunofluorescence staining of apoptosis (TUNEL) display that VEDT induced apoptosis in (Mia-GFP) cells compared to vehicle (Veh) after 24?h and apoptosis was rescued in (Mia-FLIP) cells compared to vehicle (Veh) (n?=?3)

cmerp October 22, 2021

CF?=?cleaved fragment (n?=?3) and (E) Immunofluorescence staining of apoptosis (TUNEL) display that VEDT induced apoptosis in (Mia-GFP)...

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Jean Pierre Haelters, Paul Alain Jaffrs synthetized the lipid inhibitor of SK3 route, Ohmline

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• Serotonin Transporters

Jean Pierre Haelters, Paul Alain Jaffrs synthetized the lipid inhibitor of SK3 route, Ohmline

cmerp October 21, 2021

Jean Pierre Haelters, Paul Alain Jaffrs synthetized the lipid inhibitor of SK3 route, Ohmline. alkyl-lipid Ohmline, which...

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To that end, we treated BV-2 cells with the adrenoceptor agonist isoproterenol or PGE2 and PGN, and then determined IL-10 concentrations from your supernantants

3 min read

• LTA4 Hydrolase

To that end, we treated BV-2 cells with the adrenoceptor agonist isoproterenol or PGE2 and PGN, and then determined IL-10 concentrations from your supernantants

cmerp October 19, 2021

To that end, we treated BV-2 cells with the adrenoceptor agonist isoproterenol or PGE2 and PGN, and...

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Genes overlapping between current DEGs and all genes differentially expressed between ethanol and control groups from your 2016 study were also under-represented (14 out of 552; < 0

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• DNA Ligases

Genes overlapping between current DEGs and all genes differentially expressed between ethanol and control groups from your 2016 study were also under-represented (14 out of 552; < 0

cmerp October 18, 2021

Genes overlapping between current DEGs and all genes differentially expressed between ethanol and control groups from your...

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