April 23, 2025

EP1-4 Receptors

(E) SE-S induced concentration-dependent IL-6 production in individual whole bloodstream, (F) neutralizing anti-TLR2 polyclonal Abs, however, not anti-TLR4 polyclonal Abs, blunted SE-S-induced IL-6 in individual whole bloodstream
3 min read

(E) SE-S induced concentration-dependent IL-6 production in individual whole bloodstream, (F) neutralizing anti-TLR2 polyclonal Abs, however, not anti-TLR4 polyclonal Abs, blunted SE-S-induced IL-6 in individual whole bloodstream

cmerp June 14, 2022
(E) SE-S induced concentration-dependent IL-6 production in individual whole bloodstream, (F) neutralizing anti-TLR2 polyclonal Abs, however, not...
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Here, finding that inhibitory neurotransmitter glycine does not activate KCNQs, we re-engineered it in silico to expose expected KCNQ-opening properties, screened by in silico docking, then validated the hits in vitro
3 min read

Here, finding that inhibitory neurotransmitter glycine does not activate KCNQs, we re-engineered it in silico to expose expected KCNQ-opening properties, screened by in silico docking, then validated the hits in vitro

cmerp October 25, 2021
Here, finding that inhibitory neurotransmitter glycine does not activate KCNQs, we re-engineered it in silico to expose...
Read More

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Proteins scaffold antigens carrying the V1V2 locations from HIV-1 subtypes A, B, C, CRF01_AE or D were assayed in pilot research, and 6 were selected to assess cross-reactive Stomach muscles in the plasma from the initial RV144 case-control cohort (41 infected vaccinees, 205 frequency-matched uninfected vaccinees, and 40 placebo recipients) using ELISA and a binding Stomach multiplex assay

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But when analyzing the 5 different proteins (LTAg, stAg, VP1, VP2, and agnoprotein) that were present as peptides around the microarray, it was surprising to see that antibody responses to stAg peptide were significantly elevated (p?=?3
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But when analyzing the 5 different proteins (LTAg, stAg, VP1, VP2, and agnoprotein) that were present as peptides around the microarray, it was surprising to see that antibody responses to stAg peptide were significantly elevated (p?=?3

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One efficient method is replica-exchange molecular dynamics simulation (Sugita and Okamoto 1999)
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One efficient method is replica-exchange molecular dynamics simulation (Sugita and Okamoto 1999)

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This work was supported partly with a Marie Curie Development Host Fellowship (HPMD-CT-2000-00034, to M
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This work was supported partly with a Marie Curie Development Host Fellowship (HPMD-CT-2000-00034, to M

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