October 10, 2024

Day: September 28, 2024

Of the six individuals who received CAR T-cells after blinatumomab, three were alive in CR at last follow-up, two initially responded to blinatumomab and died after relapse, and one received CAR T-cells like a non-responder to blinatumomab and died after CAR T-cell treatment
3 min read

Of the six individuals who received CAR T-cells after blinatumomab, three were alive in CR at last follow-up, two initially responded to blinatumomab and died after relapse, and one received CAR T-cells like a non-responder to blinatumomab and died after CAR T-cell treatment

cmerp September 28, 2024
Of the six individuals who received CAR T-cells after blinatumomab, three were alive in CR at last...
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(B) Proliferation with increasing focus of ruxolitinib in accordance with proliferation in the current presence of DMSO control is depicted for Ba/F3 cells transduced with EPOR coexpressing either Jak2 WT, Jak2S523L, Jak2V617F, or Jak2K539L
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(B) Proliferation with increasing focus of ruxolitinib in accordance with proliferation in the current presence of DMSO control is depicted for Ba/F3 cells transduced with EPOR coexpressing either Jak2 WT, Jak2S523L, Jak2V617F, or Jak2K539L

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RhoGDI, which is a universally expressed RhoGDI, was stained using anti-RhoGDI antibody (sc-360) like a loading control
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RhoGDI, which is a universally expressed RhoGDI, was stained using anti-RhoGDI antibody (sc-360) like a loading control

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Dynabeads proteins G was added and incubated for 2 then?h
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Dynabeads proteins G was added and incubated for 2 then?h

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In experiments where RNAi was less efficient, hardly any reduction in nuclear export could be observed
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In experiments where RNAi was less efficient, hardly any reduction in nuclear export could be observed

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